Euphorbia tortirama is from the Northern Province of South Africa. These plants are from material originally collected at Greyton, in the Western Cape Province. This species is one of the spiny stemmed medusoid species that is highly valued by collectors. The relatively thick stems are twisted with sparse spines, and these plants differ from typical E. tortirama in that the branches are 4-angled branches. The cyathia are yellow. These plants are seedlings in 2-inch pots.